Low back pain is a prevalent condition that affects many people worldwide and can significantly impact their lives and the healthcare system. One of the most common causes of low back pain is degenerative disc disease, which occurs when the discs between the bones in the spine start to break down and become damaged.

Recent research shows that this breakdown of the discs is not just a simple case of wear and tear but rather a complex process that involves changes in the cells and the environment inside the discs. As we age and experience other factors like abnormal stress on the spine, the discs don’t receive enough oxygen, nutrients, and waste removal. This leads to a buildup of acid and other harmful substances inside the discs, which can cause pain and further damage.

To help treat this condition, scientists are looking at using substances naturally found in the body, called orthobiologics, to promote the healing and regeneration of the damaged discs. Two examples of orthobiologics are platelet-rich plasma (PRP) and platelet lysate, derived from a person’s blood.

PRP is a concentrated mixture of growth factors and other beneficial substances that can help stimulate the repair and regrowth of damaged tissue. When injected into the affected discs, PRP may help to boost the production of important components that make up the discs, such as collagen and proteoglycans. PRP also has anti-inflammatory properties, which can help to reduce pain and swelling associated with degenerative disc disease.

Platelet lysate, another substance derived from platelets, has also shown potential in treating degenerative disc disease. Like PRP, platelet lysate contains a variety of growth factors and other substances that can promote tissue repair and reduce inflammation. In animal studies, platelet lysate has been shown to stimulate the growth and development of disc cells and enhance the production of the substances that make up the discs.

While the use of orthobiologics to treat degenerative disc disease and low back pain is still relatively new, the available evidence suggests that these substances may offer a promising alternative to traditional treatments like surgery or long-term medication use. Using the body’s healing mechanisms, orthobiologics may help repair and regenerate damaged disc tissue, reduce pain and inflammation, and improve overall function in people with low back pain caused by degenerative disc disease.

However, more research is needed to fully understand the potential benefits and limitations of orthobiologics in treating degenerative disc disease and low back pain. Large-scale studies must confirm these substances’ safety and effectiveness and determine the best dosing and administration methods. Long-term follow-up studies are also necessary to assess how long the treatment effects last and identify any potential side effects associated with orthobiologics.

At Columbia Pain Management, we understand the evolving science of pain and provide innovative treatments to help you reclaim your life. If you’re trapped by unrelenting pain, our experts guide you toward healing and fulfillment. Call 503-654-5636 or 541-205-0173 to schedule an appointment. We’re committed to helping you find relief and improve your quality of life. Let us assist you in taking the first step toward a pain-free life.